KMID : 1128320160140020027
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Electrolytes & Blood Pressure 2016 Volume.14 No. 2 p.27 ~ p.30
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Severe Hypernatremia Caused by Acute Exogenous Salt Intake Combined with Primary Hypothyroidism
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Jung Woo-Jin
Park Su-Min Park Jong-Man Rhee Ha-Rin Kim Il-Young Lee Dong-Won Lee Soo-Bong Seong Eun-Young Kwak Ihm-Soo Song Sang-Heon
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Abstract
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This report describes a case of severe hypernatremia with a serum sodium concentration of 188.1mmol/L caused by exogenous salt intake. A 26-year-old man diagnosed with Crohn¡¯s disease 5 years previously visited our clinic due to generalized edema and personality changes, with aggressive behavior. He had compulsively consumed salts, ingesting approximately 154 g of salt over the last 4 days. Despite careful fluid management that included not only hypotonic fluid therapy for 8 hours but also hypertonic saline administration, his serum sodium level decreased sharply at 40.6 mmol/L; however, it returned to normal within 72-hour of treatment without any neurological deficits. Primary hypothyroidism was also diagnosed. He was discharged after 9 days from admission, with a stable serum sodium level. We have described the possibility of successful treatment in a patient with hypernatremia caused by acute salt intoxication without sustained hypotonic fluid therapy.
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KEYWORD
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Hypernatremia, Salt, Primary hypothyroidism, Crohn¡¯s disease
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